Neuroscience/Neuropathology Trainers

The graduate faculty and a brief statement of their research interests are listed below. Many of these individual research programs are funded by awards from a variety of funding resources. Inquiries regarding space in a laboratory and availability of research support should be directed to the individual faculty member.

Portrait of Craig S. Atwood, PhD
Medicine
Research Summary: Aging; endocrinology; development; degenerative diseases of the central nervous system
Portrait of Barbara Bendlin, PhD
Medicine
Research Summary: Aging; Alzheimer's disease, Neurobiology of Disease, Behavior and Cognition
Portrait of Corinna Burger, PhD
Neurology
Research Summary: Molecular Neuroscience, Behavior: Cognition and aging, Neurobiology of Disease, synaptic plasticity
Portrait of Marina Emborg, MD, PhD
Medical Physics
Research Summary: Parkinson’s disease
Portrait Zsuzsanna Fabry, PhD
Pathology and Laboratory Medicine
Research Summary: Mechanisms of neuroinflammation in autoimmunity, infection or traumas of the Central Nervous System.
Portrait of Lian-Wang Guo, MS, PhD
Surgery
Research Summary: Mechanisms of restenosis, proliferation and inflammation, retinal neurodegeneration and regeneration, neural progenitor/stem cells.
Medical Microbiology and Immunology
Research Summary: We study the host/pathogen interactions for the parasite Toxoplasma gondii in a mouse model
Cell and Regenerative Biology
Research Summary: Cardiac regeneration, Transcriptional control of cardiomyocyte cell cycle, Nerve regulation of heart regeneration
Portrait of Albee Messing, VMD, PhD
Comparative Biosciences
Research Summary: Alexander disease; developmental neuropathology; molecular neurobiology
Portrait of Robert Nickells, PhD
Ophthalmology and Visual Sciences
Research Summary: Glaucoma, Neurodegeneration, Complex Genetics, Neuronal Apoptosis
Medicine
Research Summary: Alzheimer’s disease, neuroimaging, lifestyle, genetics, cognitive resilience
Portrait of Luigi Puglielli, MD, PhD
Medicine
Research Summary: Molecular mechanisms of neurodevelopment and neurodegeneration
Pathology and Laboratory Medicine
Research Summary: Cell Biology of neuronal trafficking in physiology and neurodegenerative diseases
Comparative Biosciences
Research Summary: Regulation of Neural Stem Cells in Disorders of Myelination
Ophthalmology and Visual Sciences
Research Summary: The role of cell-cell and cell-matrix interactions in vascular development and neovascularization
Chemical and Biological Engineering
Research Summary: We are interested in the discovery of novel transport systems and cognate antibody targeting molecules, and we design high throughput selections that serve this purpose. Along these lines, we are also working to optimize the process for producing large amounts of therapeutic antibodies and proteins to meet the eventual demands of clinical application. We are also interested in developing in vitro models of the BBB that accurately mimic the in vivo characteristics of the BBB.
Portrait of Masatoshi Suzuki, PhD, DVM
Comparative Biosciences
Research Summary: Application of stem cells to developmental modeling and cell-based therapy
Portrait of Robert G. Thorne, PhD
Pharmacy
Research Summary: CNS drug delivery; transport mechanisms in brain tissue; neurodegenerative disease, multiple sclerosis & stroke
Tyler Ulland
Pathology and Laboratory Medicine
Research Summary: The innate immune response to neurodegenerative disease has been understudied until very recently. The Ulland Lab focuses on the role of the innate immune response and more specifically microglial response in AD. We have established the tools and models to effectively work on the neuroimmune response during AD. The ultimate goal of our group is to provide a more thorough understanding of the molecular and metabolic changes in immune cells that precede and follow AD onset, information that will be important in intelligently designing therapeutic strategies.
Portrait of Raghu Vemuganti, PhD
Neurosurgery
Research Summary: Development: Plasticity and Repair, Molecular Neuroscience, Neurobiology of Disease
Comparative Biosciences
Research Summary: Regulation of microglial gene transcription and signal transduction mechanisms in paradigms of hypoxia; Epigenetic modulation of microglial phenotypes; Maternal hypoxia-induced reprogramming of fetal offspring microglia and adult behavior; Sex differences in microglial function and gene expression
Neuroscience
Research Summary: Stem Cell Approaches to Neural Degeneration and Regeneration
Portrait of Xinyu Zhao, PhD
Neuroscience
Research Summary: The molecular mechanisms that regulate neural stem cells and neurodevelopment with the goal of applying this knowledge in the treatment of neurological disorders and injuries