Arjang Djamali, MD

Portrait of Arjang Djamali, MD
Associate Professor
5142 MFCB
1685 Highland Ave
Madison, WI 53792
(608) 270-5681
Focus Groups: 
Signal Transduction
MD, Montpellier Medical School, Montpellier, France
Research Summary: 
The cellular and molecular mechanisms of fibrogenesis in native and transplant kidney disease
Research Detail: 

We are interested in examining the cellular and molecular mechanisms of fibrogenesis in native and transplant kidney disease. To this end, we use in vitro, animal and human studies. We are currently investigating the role of Nox and heat shock protein 27 in the pathogenesis of kidney injury. Study models are rat proximal tubular epithelial cells (NRK52E cell line) and murine models of kidney transplantation, unilateral ureteral obstruction and 5/6th nephrectomy. Ongoing translational studies are examining these processes in patients with chronic kidney disease and chronic allograft nephropathy.

Selected Publications: 
The Feared Five Fungal Infections in Kidney Transplant Recipients: A Single Center20-year Experience. Parajuli S, Wick A, Pandeya S, Astor BC, Smith J, Djamali A, Mandelbrot DA. Clin Transplant. 2018 May 21:e13289. doi: 10.1111/ctr.13289. [Epub ahead of print] PMID: 29782660
BK Viremia is Not Associated with Adverse Outcomes in the Absence of BK Nephropathy. Hertz-Tang AL, Astor BC, Mandelbrot DA, Mohamed MA, Djamali A, Parajuli S. Clin Transplant. 2018 May 17:e13283. doi: 10.1111/ctr.13283. [Epub ahead of print] PMID: 29774593
Rituximab and Monitoring Strategies for Late Antibody-Mediated Rejection After Kidney Transplantation. Parajuli S, Mandelbrot DA, Muth B, Mohamed M, Garg N, Aziz F, Redfield RR, Zhong W, Astor BC, Djamali A. Transplant Direct. 2017 Oct 27;3(12):e227. doi: 10.1097/TXD.0000000000000746. eCollection 2017 Dec. PMID: 29536028
Which is more nephrotoxic for kidney transplants: BK nephropathy or rejection? Parajuli S, Astor BC, Kaufman D, Muth B, Mohamed M, Garg N, Djamali A, Mandelbrot DA. Clin Transplant. 2018 Apr;32(4):e13216. doi: 10.1111/ctr.13216. Epub 2018 Feb 23. PMID: 29394515
Higher Pretransplantation Hemoglobin A1c Is Associated With Greater Risk of Posttransplant Diabetes Mellitus. Shin JI, Palta M, Djamali A, Astor BC. Kidney Int Rep. 2017 Jun 22;2(6):1076-1087. doi: 10.1016/j.ekir.2017.06.006. eCollection 2017 Nov. PMID: 29270516
Kidney Transplant Recipients With Primary Membranous Glomerulonephritis Have a Higher Risk of Acute Rejection ComparedWith Other Primary Glomerulonephritides. Singh T, Astor B, Zhong W, Mandelbrot D, Djamali A, Panzer S. Transplant Direct. 2017 Oct 18;3(11):e223. doi: 10.1097/TXD.0000000000000736. eCollection 2017 Nov. PMID: 29184911
Evaluation of renal metabolic response to partial ureteral obstruction with hyperpolarized 13 C MRI. Niles DJ, Gordon JW, Huang G, Reese S, Adamson EB, Djamali A, Fain SB. NMR Biomed. 2018 Jan;31(1). doi: 10.1002/nbm.3846. Epub 2017 Nov 12. PMID: 29130537
Defining the phenotype of antibody-mediated rejection in kidney transplantation: Advances in diagnosis of antibody injury. Garg N, Samaniego MD, Clark D, Djamali A. Transplant Rev (Orlando). 2017 Oct;31(4):257-267. doi: 10.1016/j.trre.2017.08.005. Epub 2017 Aug 15. Review. PMID: 28882367
Seasonality of mortality and graft failure among kidney transplant recipients in the US -a retrospective study. Astor BC, Melamed ML, Mandelbrot DA, Djamali A. Transpl Int. 2018 Mar;31(3):293-301. doi: 10.1111/tri.13047. Epub 2017 Sep 26. PMID: 28871657
Utility of protocol kidney biopsies for de novo donor-specific antibodies. Parajuli S, Reville PK, Ellis TM, Djamali A, Mandelbrot DA. Am J Transplant. 2017 Dec;17(12):3210-3218. doi: 10.1111/ajt.14466. Epub 2017 Sep 26. PMID: 28805293