Feyza Engin, PhD

Portrait of Feyza Engin, PhD
Assistant Professor
Biomolecular Chemistry
Address: 
6260B Biochemical Sciences Building
440 Henry Mall
Madison, WI 53706
Telephone: 
(608) 262-8667
Focus Groups: 
Immunology/Immunopathology
Signal Transduction
Education: 
PhD, Baylor College of Medicine
Research Summary: 
Type 1 diabetes (T1D) results from the destruction of the insulin-secreting b-cells by an immune mediated process. The increasing incidence of type 1 diabetes around the word, especially among children, has been of great concern.
Selected Publications: 
The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice.Fenske RJ, Cadena MT, Harenda QE, Wienkes HN, Carbajal K, Schaid MD, Laundre E, Brill AL, Truchan NA, Brar H, Wisinski J, Cai J,Graham TE, Engin F, Kimple ME.Endocrinology. 2017 Jun 1;158(6):1645-1658. doi: 10.1210/en.2016-1700.PMID: 28419211
ER stress and development of type 1 diabetes.Engin F.J Investig Med. 2016 Jan;64(1):2-6. Review.PMID: 26230493
Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms.Brozzi F, Nardelli TR, Lopes M, Millard I, Barthson J, Igoillo-Esteve M, Grieco FA, Villate O, Oliveira JM, Casimir M, Bugliani M, Engin F, Hotamisligil GS, Marchetti P, Eizirik DL.Diabetologia. 2015 Oct;58(10):2307-16. doi: 10.1007/s00125-015-3669-6. Epub 2015 Jun 23.PMID: 26099855